Viral-mediated Gene Transfer System

The inventors were the first to propose the use of viral DNA vectors as a general way to transfer genes into mammalian cells. They were also the first to directly administer a human gene in vivo and obtain expression in an experimental animal. Their viral-mediated gene transfer system is now the basic technique that many companies have adopted over the past decade.

The technology is protected by U.S. Patent No. 5,672,344.

Inventors

William N. Kelley, Thomas Palella and Myron Levine, University of Michigan