Viral-mediated Gene Transfer System

The inventors were the first to propose the use of viral DNA vectors as a general way to transfer genes into mammalian cells. They also were the first to directly administer a human gene in vivo and obtain expression in an experimental animal. Their viral-mediated gene transfer system is now the basic technique that many companies have adopted over the past decade.

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Inventors

• William N. Kelley, University of Michigan
• Thomas Palella, University of Michigan
• Myron Levine, University of Michigan

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US Patent

5,672,344